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Although these data show a favorable riskbenefit profile for GLP-1RA, there are differences between individual drugs with respect to their effect on cardiorenal outcomes in the separate trials

3.2 Glycaemic response In the prediabetes group, treatment with linagliptin 5 mg once-daily for 12 weeks significantly reduced HbA1c from baseline in the high GLP-1 group [LS-mean change from baseline -0.33% (95% CI -0.48, -0.18)

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